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Metabolic Research

5-Amino-1MQ

CAS 685079-15-6Research Use Only

A small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor used in studies of NAD+ salvage, adipocyte metabolism, and cellular energy-signaling research. For laboratory research use only.

$55$38.50WITH CODE FALL
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$55.00
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Compound Information

Technical specifications

Molecular Profile

What is this compound?

5-Amino-1MQ is a selective, membrane-permeable inhibitor of nicotinamide N-methyltransferase (NNMT), supplied as a lyophilized powder for in vitro laboratory research use only. It is studied in the peer-reviewed literature as a chemical probe of the NNMT/NAD+ salvage axis, and is investigated in research models for its role in adipocyte metabolic signaling and cellular energy homeostasis pathways.

Research applications: Commonly used in NNMT enzyme-inhibition studies, NAD+ salvage-pathway research, and metabolic-signaling research applications.

Type
Nicotinamide N-methyltransferase (NNMT) inhibitor (small molecule)
CAS Number
685079-15-6
Molecular Weight
159.21 g/mol
Formula
C10H11N2+
Sequence
Quinolinium small molecule; not a peptide
PubChem Database
Storage Requirements

Stability Information

Protect from lightTemperature-sensitive
Lyophilized (powder)-20°C · stable long-term
In solution2-8°C · protect from light

Sources & References

Peer-reviewed research

Biochemical pharmacology
2018PMID 29155147DOI 10.1016/j.bcp.2017.11.007
Neelakantan H, Vance V, Wetzel MD, et al.
View on PubMed
Scientific reports
Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
2022PMID 35013352DOI 10.1038/s41598-021-03670-5
Dimet-Wiley A, Wu Q, Wiley JT, et al.
View on PubMed
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells
2021PMID 33645410DOI 10.1080/01443615.2020.1854696
Akar S, Duran T, Azzawri AA, et al.
View on PubMed

Some titles are not reproduced here. Ventra Sciences sells for research use only and does not republish therapeutic indications; open the record on PubMed to read the full citation.

References are provided for qualified researchers as a starting point for literature review. Ventra Sciences makes no claims about the contents of cited works.

For research use only

This product is intended strictly for in vitro laboratory research by qualified professionals. It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics. Ventra Sciences makes no medical claims regarding any compound sold. All purchasers acknowledge they will use this product solely for research purposes.

This compound has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease. All use must comply with applicable institutional, local, and federal regulations.

By purchasing from Ventra Sciences, the buyer affirms they are a qualified researcher or institution. All sales are final. The purchaser assumes full responsibility for handling, use, and regulatory compliance.

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