Peptide

ARA-290

Name: ARA-290
Brand: Ventra Sciences
Availability: InStock

CAS 1208243-50-8 Research Use Only

A non-erythropoietic 11-amino-acid peptide engineered from erythropoietin, studied for its role in innate repair receptor (IRR) signaling and neuroimmune research. For laboratory research use only.

Dosage

Quantity

$65.00

Bundle & save

Free priority shipping on $250+

Third-party tested

U.S.-synthesized & shipped

Discreet packaging

Free Amino H2O on orders $150+

Compound Information

Technical specifications

Molecular Profile

What is this compound?

Type: Non-erythropoietic erythropoietin-derived peptide
CAS Number: 1208243-50-8
Molecular Weight: 1257.3 g/mol
Formula: C51H84N16O21
Amino Acids: 11
Sequence: Erythropoietin helix-B-derived 11-mer

PubChem Database

Storage Requirements

Stability Information

Protect from light Temperature-sensitive

Lyophilized (powder) -20°C · stable long-term

Reconstituted 2-8°C · use within 28 days

Sources & References

Peer-reviewed research

Toxicology in Vitro

An engineered non-erythropoietic erythropoietin-derived peptide, ARA290, attenuates doxorubicin induced genotoxicity and oxidative stress

2020 PMID 32335150 DOI 10.1016/j.tiv.2020.104864

Shokrzadeh M, Etebari M, Ghassemi-Barghi N

View on PubMed

Pharmacology & Therapeutics

Flipping the molecular switch for innate protection and repair of tissues: Long-lasting effects of a non-erythropoietic small peptide engineered from erythropoietin

2015 PMID 25728128 DOI 10.1016/j.pharmthera.2015.02.005

Collino M, Thiemermann C, Cerami A, et al.

View on PubMed

Frontiers in Immunology

Targeting the innate repair receptor axis via erythropoietin or pyroglutamate helix B surface peptide attenuates hemolytic-uremic syndrome in mice

2022 PMID 36211426 DOI 10.3389/fimmu.2022.1010882

Dennhardt S, Pirschel W, Wissuwa B, et al.

View on PubMed

References are provided for qualified researchers as a starting point for literature review. Ventra Sciences makes no claims about the contents of cited works.

ARA-290, also known as cibinetide, is an 11-amino-acid peptide derived from the helix-B domain of erythropoietin, supplied as a lyophilized powder for in vitro laboratory research use only. It is engineered to engage the innate repair receptor (EPOR-beta common receptor complex) without erythropoietic activity, and appears in the peer-reviewed literature in studies of tissue-repair signaling, neuroimmune pathways, and small-fiber research models.

Product Description

Sequence derived from the helix B region of erythropoietin; also referred to as cibinetide in the literature
Selective for the heteromeric innate repair receptor (EPOR / beta-common CD131) rather than the classical erythropoietin receptor
Described as non-erythropoietic in published work: it does not drive red blood cell production the way EPO does
Investigated in preclinical models of small-fiber neuropathy and tissue-injury signaling
Frequently cited in the innate-repair and neuroimmune research literature

Research Use Notes

Supplied as lyophilized powder in a sealed vial
Requires reconstitution before use; Amino H2O sold separately
Appearance: white to off-white lyophilized powder
Identity and purity verified by third-party COA

Storage & Handling

Store the sealed lyophilized vial frozen (-20C) and protected from light
Keep refrigerated (2-8C) once reconstituted
Reconstituted peptide has a limited stability window; handle per laboratory SOP

Intended Use:

This compound is intended strictly for in vitro laboratory research by qualified professionals.
It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics.

Disclaimer:

This compound has not been evaluated by the FDA.
It is not intended to diagnose, treat, cure, or prevent any disease.
All use must comply with applicable institutional, local, and federal regulations.

Terms of Sale:

By purchasing from Ventra Sciences, the buyer affirms they are a qualified researcher or institution.
All sales are final. The purchaser assumes full responsibility for handling, use, and regulatory compliance.

Research applications: Commonly used in innate repair receptor signaling studies, neuroimmune research, and tissue-repair pathway research applications.

For laboratory research use only. Not a drug, cosmetic, supplement, or food. Not for human or animal consumption.

This product is intended strictly for in vitro laboratory research by qualified professionals. It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics. Ventra Sciences makes no medical claims regarding any compound sold. All purchasers acknowledge they will use this product solely for research purposes.