Endocrine / Growth Research

CJC-1295 No DAC

Name: CJC-1295 No DAC
Brand: Ventra Sciences
Availability: InStock

CAS 863288-34-0 Research Use Only

A growth hormone releasing hormone (GHRH) analog based on the GRF(1-29) sequence without the drug affinity complex, studied for its role in somatotroph and GH/IGF-1 axis signaling. For laboratory research use only.

Dosage

Quantity

$60.00

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Third-party tested

U.S.-synthesized & shipped

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Free Amino H2O on orders $150+

Compound Information

Technical specifications

Molecular Profile

What is this compound?

Type: GHRH (GRF 1-29) analog peptide, without drug affinity complex
CAS Number: 863288-34-0
Molecular Weight: 3367.9 g/mol
Formula: C152H252N44O42
Amino Acids: 29
Sequence: Modified GRF(1-29) analog

PubChem Database

Storage Requirements

Stability Information

Protect from light Temperature-sensitive

Lyophilized (powder) -20°C · stable long-term

Reconstituted 2-8°C · use within 28 days

Sources & References

Peer-reviewed research

The Journal of clinical endocrinology and metabolism

Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults

2006 PMID 16352683 DOI 10.1210/jc.2005-1536

Teichman SL, Neale A, Lawrence B, et al.

View on PubMed

The Journal of clinical endocrinology and metabolism

Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog

2006 PMID 17018654 DOI 10.1210/jc.2006-1702

Ionescu M, Frohman LA

View on PubMed

Endocrinology

Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog

2005 PMID 15817669 DOI 10.1210/en.2004-1286

Jetté L, Léger R, Thibaudeau K, et al.

View on PubMed

References are provided for qualified researchers as a starting point for literature review. Ventra Sciences makes no claims about the contents of cited works.

CJC-1295 No DAC is a synthetic growth hormone releasing hormone (GHRH) analog built on the GRF(1-29) sequence, supplied without the drug affinity complex (DAC) albumin-binding modification, and supplied as a lyophilized powder for in vitro laboratory research use only. The CJC-1295 GHRH-analog family is characterized in the peer-reviewed literature for its engagement of the GRF receptor and its role in GH/IGF-1 axis and somatotroph pulsatility research.

Product Description

Analog of the first 29 residues of growth hormone-releasing hormone (GHRH 1-29), the shortest fully active GHRH fragment
Carries four substitutions (D-Ala2, Gln8, Ala15, Leu27) that increase resistance to enzymatic degradation
'No DAC' denotes the absence of the Drug Affinity Complex linker, giving a far shorter plasma half-life than DAC-modified versions
Binds the GHRH receptor on pituitary somatotrophs in preclinical models
Widely referenced in the growth-hormone secretagogue research literature

Research Use Notes

Supplied as lyophilized powder in a sealed vial
Requires reconstitution before use; Amino H2O sold separately
Appearance: white lyophilized cake or powder
Purity verified by third-party COA

Storage & Handling

Store the sealed lyophilized vial frozen (-20C), protected from light
Keep refrigerated (2-8C) once reconstituted
Do not repeatedly freeze and thaw reconstituted material

Intended Use:

This compound is intended strictly for in vitro laboratory research by qualified professionals.
It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics.

Disclaimer:

This compound has not been evaluated by the FDA.
It is not intended to diagnose, treat, cure, or prevent any disease.
All use must comply with applicable institutional, local, and federal regulations.

Terms of Sale:

By purchasing from Ventra Sciences, the buyer affirms they are a qualified researcher or institution.
All sales are final. The purchaser assumes full responsibility for handling, use, and regulatory compliance.

Research applications: Commonly used in GHRH receptor signaling studies, somatotroph pulsatility research, and GH/IGF-1 axis research applications.

For laboratory research use only. Not a drug, cosmetic, supplement, or food. Not for human or animal consumption.

This product is intended strictly for in vitro laboratory research by qualified professionals. It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics. Ventra Sciences makes no medical claims regarding any compound sold. All purchasers acknowledge they will use this product solely for research purposes.