Peptide

KPV

CAS 67727-97-3 Research Use Only

The C-terminal tripeptide of alpha-MSH (Lys-Pro-Val), studied in the literature for its role in melanocortin-derived inflammatory-signaling pathways. For laboratory research use only.

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$60.00
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Compound Information

Technical specifications

Molecular Profile

What is this compound?

Type
alpha-MSH (11-13) C-terminal tripeptide
CAS Number
67727-97-3
Molecular Weight
342.43 g/mol
Formula
C16H30N4O4
Amino Acids
3
Sequence
Lys-Pro-Val
PubChem Database
Storage Requirements

Stability Information

Protect from light Temperature-sensitive
Lyophilized (powder) -20°C · stable long-term
Reconstituted 2-8°C · use within 28 days

Sources & References

Peer-reviewed research

Inflammatory bowel diseases
Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease
2008 PMID 18092346 DOI 10.1002/ibd.20334
Kannengiesser K, Maaser C, Heidemann J, et al.
View on PubMed
The Journal of investigative dermatology
alpha-Melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells
2004 PMID 15102092 DOI 10.1111/j.0022-202X.2004.22404.x
Elliott RJ, Szabo M, Wagner MJ, et al.
View on PubMed
Molecular therapy : the journal of the American Society of Gene Therapy
Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis
2017 PMID 28143741 DOI 10.1016/j.ymthe.2016.11.020
Xiao B, Xu Z, Viennois E, et al.
View on PubMed

References are provided for qualified researchers as a starting point for literature review. Ventra Sciences makes no claims about the contents of cited works.

KPV is the C-terminal tripeptide fragment (11-13) of alpha-melanocyte-stimulating hormone, supplied as a lyophilized powder for in vitro laboratory research use only. It is characterized in the peer-reviewed literature as a melanocortin-derived peptide investigated in research models of inflammatory signaling, epithelial barrier research, and mucosal biology.

Product Description

  • Three-residue peptide: lysine-proline-valine
  • Corresponds to residues 11-13 of alpha-melanocyte-stimulating hormone (alpha-MSH)
  • Reported to modulate NF-kB signaling in cell models without engaging melanocortin receptors
  • Studied in mucosal, dermal, and epithelial tissue-repair research
  • Frequently referenced in the literature on melanocortin-derived peptide fragments

Research Use Notes

  • Supplied as lyophilized powder in a sealed vial
  • Requires reconstitution before use; Amino H2O sold separately
  • Appearance: white lyophilized powder
  • Identity and purity verified by third-party COA

Storage & Handling

  • Store the sealed lyophilized vial frozen (-20C), protected from light
  • Keep refrigerated (2-8C) once reconstituted
  • Short peptides are hygroscopic; keep the vial sealed until reconstitution

Intended Use:

This compound is intended strictly for in vitro laboratory research by qualified professionals.
It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics.

Disclaimer:

This compound has not been evaluated by the FDA.
It is not intended to diagnose, treat, cure, or prevent any disease.
All use must comply with applicable institutional, local, and federal regulations.

Terms of Sale:

By purchasing from Ventra Sciences, the buyer affirms they are a qualified researcher or institution.
All sales are final. The purchaser assumes full responsibility for handling, use, and regulatory compliance.

Research applications: Commonly used in melanocortin signaling studies, inflammatory-pathway research, and epithelial research applications.

For laboratory research use only. Not a drug, cosmetic, supplement, or food. Not for human or animal consumption.

This product is intended strictly for in vitro laboratory research by qualified professionals. It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics. Ventra Sciences makes no medical claims regarding any compound sold. All purchasers acknowledge they will use this product solely for research purposes.

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