Journal of Inherited Metabolic Disease
Vitamin B12, folate, and the methionine remethylation cycle-biochemistry, pathways, and regulation
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A four-component research solution of L-methionine, myo-inositol, choline and cyanocobalamin, studied in one-carbon metabolism, methyl-donor, and inositol phosphate structural research. For laboratory research use only.
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Technical specifications
Lipo-C with B12 is a four-component research solution supplied pre-mixed in a 10 mL vial for in vitro laboratory research use only. Unlike the lyophilized compounds in this catalog it requires no reconstitution. Each component is independently characterized in the peer-reviewed literature: L-methionine as the precursor of S-adenosylmethionine, described in that literature as the principal cellular methyl donor; choline as a methyl-group source feeding the same methionine cycle by way of the folate and choline shuttling pathways; cyanocobalamin as the cofactor for methionine synthase, the enzyme that remethylates homocysteine to methionine; and myo-inositol, the parent cyclitol whose phosphorylated derivatives, the inositol phosphates, are characterized in the cited structural literature as second messengers bound to signaling effector proteins.
Research applications: Commonly used in one-carbon metabolism studies, methyl-donor pathway research, and inositol phosphate structural research applications.
Peer-reviewed research
References are provided for qualified researchers as a starting point for literature review. Ventra Sciences makes no claims about the contents of cited works.
This product is intended strictly for in vitro laboratory research by qualified professionals. It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics. Ventra Sciences makes no medical claims regarding any compound sold. All purchasers acknowledge they will use this product solely for research purposes.
This compound has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease. All use must comply with applicable institutional, local, and federal regulations.
By purchasing from Ventra Sciences, the buyer affirms they are a qualified researcher or institution. All sales are final. The purchaser assumes full responsibility for handling, use, and regulatory compliance.
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