Melanotan I

Name: Melanotan I
Brand: Ventra Sciences
Price: 45.00 USD
Availability: OutOfStock

CAS 75921-69-6Research Use Only

A synthetic 13-amino-acid analog of alpha-MSH, studied in the literature for its role in melanocortin-1 receptor (MC1R) signaling and melanogenesis research. For laboratory research use only.

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Compound Information

Technical specifications

Molecular Profile

What is this compound?

Melanotan I (afamelanotide) is a synthetic linear 13-amino-acid analog of alpha-melanocyte-stimulating hormone, supplied as a lyophilized powder for in vitro laboratory research use only. It is characterized in the peer-reviewed literature as a potent melanocortin-1 receptor (MC1R) agonist with extended stability relative to native alpha-MSH, and is studied in research on melanogenesis and photoprotective signaling pathways.

Research applications: Commonly used in melanocortin-1 receptor signaling studies, melanogenesis research, and photoprotective-pathway research applications.

Type: Synthetic alpha-MSH analog (MC1R agonist)
CAS Number: 75921-69-6
Molecular Weight: 1646.8 g/mol
Formula: C78H111N21O19
Amino Acids: 13
Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

PubChem Database

Storage Requirements

Stability Information

Protect from lightTemperature-sensitive

Lyophilized (powder)-20°C · stable long-term

Reconstituted2-8°C · use within 28 days

Sources & References

Peer-reviewed research

American journal of clinical dermatology

Afamelanotide: A Review in Erythropoietic Protoporphyria

2016PMID 26979527DOI 10.1007/s40257-016-0184-6

Kim ES, Garnock-Jones KP

View on PubMed

Journal of cell science

Alpha-melanocyte stimulating hormone and its analogue Nle4DPhe7 alpha-MSH affect morphology, tyrosinase activity and melanogenesis in cultured human melanocytes

1994PMID 8175909DOI 10.1242/jcs.107.1.205

Hunt G, Todd C, Cresswell JE, et al.

View on PubMed

ACS chemical neuroscience

Comparative Functional Alanine Positional Scanning of the α-Melanocyte Stimulating Hormone and NDP-Melanocyte Stimulating Hormone Demonstrates Differential Structure-Activity Relationships at the Mouse Melanocortin Receptors

2016PMID 27135265DOI 10.1021/acschemneuro.6b00098

Todorovic A, Ericson MD, Palusak RD, et al.

View on PubMed

References are provided for qualified researchers as a starting point for literature review. Ventra Sciences makes no claims about the contents of cited works.

For research use only

This product is intended strictly for in vitro laboratory research by qualified professionals. It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics. Ventra Sciences makes no medical claims regarding any compound sold. All purchasers acknowledge they will use this product solely for research purposes.

This compound has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease. All use must comply with applicable institutional, local, and federal regulations.

By purchasing from Ventra Sciences, the buyer affirms they are a qualified researcher or institution. All sales are final. The purchaser assumes full responsibility for handling, use, and regulatory compliance.