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Endocrine / Growth Research

PEG-MGF

VSC-MGF5Research Use Only

A PEGylated form of mechano growth factor (MGF), an IGF-1 splice variant E-domain peptide studied for its role in myogenic precursor cell signaling. For laboratory research use only.

$120$84WITH CODE FALL
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$120.00
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Compound Information

Technical specifications

Molecular Profile

What is this compound?

PEG-MGF is a polyethylene-glycol-conjugated form of mechano growth factor (MGF), the E-domain peptide of the IGF-1Ec splice variant, and is supplied as a lyophilized powder for in vitro laboratory research use only. The MGF peptide is characterized in the peer-reviewed literature for its distinct pro-migratory activity on human myogenic precursor cells, separate from mature IGF-1 signaling. The PEGylation is a formulation modification intended to extend the peptide half-life; note that published literature addresses the MGF peptide itself rather than the PEGylated conjugate specifically.

Research applications: Commonly used in myogenic precursor cell research, IGF-1 splice-variant signaling studies, and tissue-repair research applications.

Type
PEGylated mechano growth factor (IGF-1Ec E-domain peptide)
Molecular Weight
2868.13 g/mol (MGF peptide; conjugate mass varies with PEG chain length)
Formula
C121H199N41O40 (MGF peptide, prior to PEG conjugation)
Amino Acids
24
Sequence
YQPPSTNKNTKSQRRKGSTFEERK (MGF / IGF-1Ec E-domain peptide, PEG-conjugated)
Storage Requirements

Stability Information

Protect from lightTemperature-sensitive
Lyophilized (powder)-20°C · stable long-term
Reconstituted2-8°C · use within 28 days

Sources & References

Peer-reviewed research

Experimental Cell Research
A new pro-migratory activity on human myogenic precursor cells for a synthetic peptide within the E domain of the mechano growth factor
2007PMID 17156777DOI 10.1016/j.yexcr.2006.10.032
Mills P, Lafrenière JF, Benabdallah BF, et al.
View on PubMed
PloS One
Insulin-like growth factor I (IGF-1) Ec/Mechano Growth factor--a splice variant of IGF-1 within the growth plate
2013PMID 24146828DOI 10.1371/journal.pone.0076133
Schlegel W, Raimann A, Halbauer D, et al.
View on PubMed
Endocrinology
Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration
2010PMID 20130113DOI 10.1210/en.2009-1217
Matheny RW Jr, Nindl BC, Adamo ML
View on PubMed

References are provided for qualified researchers as a starting point for literature review. Ventra Sciences makes no claims about the contents of cited works.

For research use only

This product is intended strictly for in vitro laboratory research by qualified professionals. It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics. Ventra Sciences makes no medical claims regarding any compound sold. All purchasers acknowledge they will use this product solely for research purposes.

This compound has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease. All use must comply with applicable institutional, local, and federal regulations.

By purchasing from Ventra Sciences, the buyer affirms they are a qualified researcher or institution. All sales are final. The purchaser assumes full responsibility for handling, use, and regulatory compliance.

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