Longevity Research

SS-31

CAS 736992-21-5 Research Use Only

A mitochondria-targeted tetrapeptide that associates with cardiolipin, studied in the literature for its role in mitochondrial bioenergetics research. For laboratory research use only.

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$70.00
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Compound Information

Technical specifications

Molecular Profile

What is this compound?

Type
Mitochondria-targeted aromatic-cationic tetrapeptide
CAS Number
736992-21-5
Molecular Weight
639.8 g/mol
Formula
C32H49N9O5
Amino Acids
4
Sequence
D-Arg-Dmt-Lys-Phe-NH2
PubChem Database
Storage Requirements

Stability Information

Protect from light Temperature-sensitive
Lyophilized (powder) -20°C · stable long-term
Reconstituted 2-8°C · use within 28 days

Sources & References

Peer-reviewed research

Journal of the American Society of Nephrology : JASN
The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin
2013 PMID 23813215 DOI 10.1681/ASN.2012121216
Birk AV, Liu S, Soong Y, et al.
View on PubMed
Proceedings of the National Academy of Sciences of the United States of America
Mitochondrial protein interaction landscape of SS-31
2020 PMID 32554501 DOI 10.1073/pnas.2002250117
Chavez JD, Tang X, Campbell MD, et al.
View on PubMed
International journal of molecular sciences
Elamipretide: A Review of Its Structure, Mechanism of Action, and Therapeutic Potential
2025 PMID 39940712 DOI 10.3390/ijms26030944
Tung C, Varzideh F, Farroni E, et al.
View on PubMed

References are provided for qualified researchers as a starting point for literature review. Ventra Sciences makes no claims about the contents of cited works.

SS-31, also known as elamipretide, is a synthetic aromatic-cationic tetrapeptide that selectively associates with cardiolipin on the inner mitochondrial membrane, and is supplied as a lyophilized powder for in vitro laboratory research use only. It is characterized in the peer-reviewed literature for its interaction with the mitochondrial protein landscape and is widely studied in research models of mitochondrial bioenergetics and cristae structure.

Product Description

  • Aromatic-cationic tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) from the Szeto-Schiller peptide series
  • Selectively associates with cardiolipin in the inner mitochondrial membrane in published biophysical studies
  • Studied for cristae architecture, electron-transport efficiency, and ROS generation in cell models
  • Investigated in preclinical models of mitochondrial dysfunction
  • Widely referenced in the bioenergetics and mitochondrial-medicine research literature

Research Use Notes

  • Supplied as lyophilized powder in a sealed vial
  • Requires reconstitution before use; Amino H2O sold separately
  • Appearance: white to off-white lyophilized powder
  • Identity and purity verified by third-party COA

Storage & Handling

  • Store the sealed lyophilized vial frozen (-20C), protected from light
  • Keep refrigerated (2-8C) once reconstituted
  • Do not repeatedly freeze and thaw reconstituted material

Intended Use:

This compound is intended strictly for in vitro laboratory research by qualified professionals.
It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics.

Disclaimer:

This compound has not been evaluated by the FDA.
It is not intended to diagnose, treat, cure, or prevent any disease.
All use must comply with applicable institutional, local, and federal regulations.

Terms of Sale:

By purchasing from Ventra Sciences, the buyer affirms they are a qualified researcher or institution.
All sales are final. The purchaser assumes full responsibility for handling, use, and regulatory compliance.

Research applications: Commonly used in mitochondrial bioenergetics studies, cardiolipin-interaction research, and cellular energy-metabolism research applications.

For laboratory research use only. Not a drug, cosmetic, supplement, or food. Not for human or animal consumption.

This product is intended strictly for in vitro laboratory research by qualified professionals. It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics. Ventra Sciences makes no medical claims regarding any compound sold. All purchasers acknowledge they will use this product solely for research purposes.

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