Metabolic Research

SLU-PP-332

CAS 303760-60-3 Research Use Only

A synthetic pan-agonist of the estrogen-related receptors (ERR alpha/beta/gamma), studied in the literature as a chemical probe of exercise-mimetic and oxidative-metabolism signaling. For laboratory research use only.

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Quantity
$65.00
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Compound Information

Technical specifications

Molecular Profile

What is this compound?

Type
Estrogen-related receptor (ERR) pan-agonist (small molecule)
CAS Number
303760-60-3
Molecular Weight
290.3 g/mol
Formula
C18H14N2O2
Sequence
Small molecule; not a peptide
PubChem Database
Storage Requirements

Stability Information

Protect from light Temperature-sensitive
Lyophilized (powder) -20°C · stable long-term
In solution 2-8°C · protect from light

Sources & References

Peer-reviewed research

ACS chemical biology
Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity
2023 PMID 36988910 DOI 10.1021/acschembio.2c00720
Billon C, Sitaula S, Banerjee S, et al.
View on PubMed
The Journal of pharmacology and experimental therapeutics
A Synthetic ERR Agonist Alleviates Metabolic Syndrome
2024 PMID 37739806 DOI 10.1124/jpet.123.001733
Billon C, Schoepke E, Avdagic A, et al.
View on PubMed
International journal of biological macromolecules
Chemical optimization of the exercise mimetic SLU-PP-332 enables insight into estrogen-related receptor signaling
2026 PMID 41850449 DOI 10.1016/j.ijbiomac.2026.151450
Okda HE, Zhao P, Hayes M, et al.
View on PubMed

References are provided for qualified researchers as a starting point for literature review. Ventra Sciences makes no claims about the contents of cited works.

SLU-PP-332 is a synthetic small-molecule pan-agonist of the estrogen-related receptors (ERR alpha, beta and gamma), supplied as a lyophilized powder for in vitro laboratory research use only. It is characterized in the peer-reviewed literature as a chemical probe that induces an ERR-alpha-dependent acute aerobic exercise response in research models, and is studied in oxidative-metabolism and metabolic-syndrome research.

Product Description

  • Small molecule, not a peptide; developed from the Saint Louis University ERR agonist chemical series
  • Pan-agonist at the estrogen-related receptors, a family of orphan nuclear receptors
  • Studied for PGC-1alpha-linked transcriptional programs and mitochondrial biogenesis in muscle cell models
  • Investigated in preclinical models of oxidative fiber-type gene expression
  • Frequently referenced in the exercise-mimetic research literature

Research Use Notes

  • Supplied as lyophilized powder in a sealed vial
  • Requires reconstitution before use; Amino H2O sold separately
  • Appearance: off-white to pale lyophilized powder
  • Identity and purity verified by third-party COA

Storage & Handling

  • Store the sealed lyophilized vial frozen (-20C), protected from light
  • Keep refrigerated (2-8C) once reconstituted
  • Reconstituted material has a limited stability window; handle per laboratory SOP

Intended Use:

This compound is intended strictly for in vitro laboratory research by qualified professionals.
It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics.

Disclaimer:

This compound has not been evaluated by the FDA.
It is not intended to diagnose, treat, cure, or prevent any disease.
All use must comply with applicable institutional, local, and federal regulations.

Terms of Sale:

By purchasing from Ventra Sciences, the buyer affirms they are a qualified researcher or institution.
All sales are final. The purchaser assumes full responsibility for handling, use, and regulatory compliance.

Research applications: Commonly used in estrogen-related receptor signaling studies, oxidative-metabolism research, and exercise-mimetic pathway research applications.

For laboratory research use only. Not a drug, cosmetic, supplement, or food. Not for human or animal consumption.

This product is intended strictly for in vitro laboratory research by qualified professionals. It is not for human or veterinary use and must not be used in food, drugs, diagnostics, or cosmetics. Ventra Sciences makes no medical claims regarding any compound sold. All purchasers acknowledge they will use this product solely for research purposes.

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